Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets

Protein:protein interactions are among the most difficult to treat molecular mechanisms of disease pathology. Cystine-dense peptides have the potential to disrupt such interactions, and are used in drug-like roles by every clade of life, but their study has been hampered by a reputation for being di...

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Detalles Bibliográficos
Autores principales: Crook, Zachary R., Sevilla, Gregory P., Friend, Della, Brusniak, Mi-Youn, Bandaranayake, Ashok D., Clarke, Midori, Gewe, Mesfin, Mhyre, Andrew J., Baker, David, Strong, Roland K., Bradley, Philip, Olson, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740061/
https://www.ncbi.nlm.nih.gov/pubmed/29269835
http://dx.doi.org/10.1038/s41467-017-02098-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740061/
https://www.ncbi.nlm.nih.gov/pubmed/29269835
http://dx.doi.org/10.1038/s41467-017-02098-8

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