Econazole nitrate inhibits PI3K activity and promotes apoptosis in lung cancer cells

The phosphatidylinositol-3-kinase (PI3K)/AKT signaling pathway plays a pivotal role in many cellular processes, including the proliferation, survival and differentiation of lung cancer cells. Thus, PI3K is a promising therapeutic target for lung cancer treatment. In this study, we applied free and o...

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Detalles Bibliográficos
Autores principales: Dong, Chao, Yang, Runxiang, Li, Hongjian, Ke, Kunbin, Luo, Chunxiang, Yang, Fang, Shi, Xi-Nan, Zhu, Ying, Liu, Xu, Wong, Man-Hon, Lin, Guimiao, Wang, Xiaomei, Leung, Kwong-Sak, Kung, Hsiang-Fu, Chen, Ceshi, Lin, Marie Chia-mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740072/
https://www.ncbi.nlm.nih.gov/pubmed/29269744
http://dx.doi.org/10.1038/s41598-017-18178-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740072/
https://www.ncbi.nlm.nih.gov/pubmed/29269744
http://dx.doi.org/10.1038/s41598-017-18178-0

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