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Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics

Current limitations to primary cell expansion led us to test whether airway epithelial cells derived from healthy children and those with asthma and cystic fibrosis (CF), co-cultured with an irradiated fibroblast feeder cell in F-medium containing 10 µM ROCK inhibitor could maintain their lineage du...

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Detalles Bibliográficos
Autores principales: Martinovich, Kelly M., Iosifidis, Thomas, Buckley, Alysia G., Looi, Kevin, Ling, Kak-Ming, Sutanto, Erika N., Kicic-Starcevich, Elizabeth, Garratt, Luke W., Shaw, Nicole C., Montgomery, Samuel, Lannigan, Francis J., Knight, Darryl A., Kicic, Anthony, Stick, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740081/
https://www.ncbi.nlm.nih.gov/pubmed/29269735
http://dx.doi.org/10.1038/s41598-017-17952-4