Prognostic and predictive role of spatially positioned tumour infiltrating lymphocytes in metastatic HER2 positive breast cancer treated with trastuzumab

Disease outcomes of HER2+ breast cancers have dramatically changed after targeted therapies, such as trastuzumab, came to clinical practice but predictive factors for trastuzumab sensitivity and resistance are frequently unknown. Current work included metastatic breast cancer patients (n = 48), who...

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Detalles Bibliográficos
Autores principales: Honkanen, Tiia J., Moilanen, Tiina, Karihtala, Peeter, Tiainen, Satu, Auvinen, Päivi, Väyrynen, Juha P., Mäkinen, Markus, Koivunen, Jussi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740084/
https://www.ncbi.nlm.nih.gov/pubmed/29269742
http://dx.doi.org/10.1038/s41598-017-18266-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740084/
https://www.ncbi.nlm.nih.gov/pubmed/29269742
http://dx.doi.org/10.1038/s41598-017-18266-1

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