Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions

Covalently locking interacting proteins in situ is an attractive strategy for addressing the challenge of identifying weak and transient protein interactions, yet it is demanding to execute chemical reactions in live systems in a biocompatible, specific, and autonomous manner. Harnessing proximity-e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Bing, Tang, Shibing, Ma, Cheng, Li, Shang-Tong, Shao, Guang-Can, Dang, Bobo, DeGrado, William F., Dong, Meng-Qiu, Wang, Peng George, Ding, Sheng, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740110/
https://www.ncbi.nlm.nih.gov/pubmed/29269770
http://dx.doi.org/10.1038/s41467-017-02409-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740110/
https://www.ncbi.nlm.nih.gov/pubmed/29269770
http://dx.doi.org/10.1038/s41467-017-02409-z

Ejemplares similares