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Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions
Covalently locking interacting proteins in situ is an attractive strategy for addressing the challenge of identifying weak and transient protein interactions, yet it is demanding to execute chemical reactions in live systems in a biocompatible, specific, and autonomous manner. Harnessing proximity-e...
Autores principales: | Yang, Bing, Tang, Shibing, Ma, Cheng, Li, Shang-Tong, Shao, Guang-Can, Dang, Bobo, DeGrado, William F., Dong, Meng-Qiu, Wang, Peng George, Ding, Sheng, Wang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740110/ https://www.ncbi.nlm.nih.gov/pubmed/29269770 http://dx.doi.org/10.1038/s41467-017-02409-z |
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