Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation

Extension of the serum half-life is an important issue in developing new therapeutic proteins and expanding applications of existing therapeutic proteins. Conjugation of fatty acid, a natural human serum albumin ligand, to a therapeutic protein/peptide was developed as a technique to extend the seru...

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Detalles Bibliográficos
Autores principales: Cho, Jinhwan, Lim, Sung In, Yang, Byung Seop, Hahn, Young S., Kwon, Inchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740134/
https://www.ncbi.nlm.nih.gov/pubmed/29269881
http://dx.doi.org/10.1038/s41598-017-18029-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740134/
https://www.ncbi.nlm.nih.gov/pubmed/29269881
http://dx.doi.org/10.1038/s41598-017-18029-y

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