Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells

The role of glutaminolysis in providing metabolites to support tumour growth is well-established, but the involvement of glutamine metabolism in invasive processes is yet to be elucidated. Here we show that normal mammary epithelial cells consume glutamine, but do not secrete glutamate. Indeed, low...

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Detalles Bibliográficos
Autores principales: Dornier, Emmanuel, Rabas, Nicolas, Mitchell, Louise, Novo, David, Dhayade, Sandeep, Marco, Sergi, Mackay, Gillian, Sumpton, David, Pallares, Maria, Nixon, Colin, Blyth, Karen, Macpherson, Iain R., Rainero, Elena, Norman, Jim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740148/
https://www.ncbi.nlm.nih.gov/pubmed/29269878
http://dx.doi.org/10.1038/s41467-017-02101-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740148/
https://www.ncbi.nlm.nih.gov/pubmed/29269878
http://dx.doi.org/10.1038/s41467-017-02101-2

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