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Mesenchymal Stem Cell-Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis

We evaluated the therapeutic potential of mesenchymal stem cell-conditioned medium (CM-MSC) as an alternative to cell therapy in an antigen-induced model of arthritis (AIA). Disease severity and cartilage loss were evaluated by histopathological analysis of arthritic knee joints and immunostaining o...

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Detalles Bibliográficos
Autores principales: Kay, Alasdair G., Long, Grace, Tyler, George, Stefan, Andrei, Broadfoot, Stephen J., Piccinini, Anna M., Middleton, Jim, Kehoe, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740178/
https://www.ncbi.nlm.nih.gov/pubmed/29269885
http://dx.doi.org/10.1038/s41598-017-18144-w