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Minocycline protects against delayed cerebral ischemia after subarachnoid hemorrhage via matrix metalloproteinase‐9 inhibition
OBJECTIVE: Delayed cerebral ischemia (DCI) is an independent risk factor for poor outcome after aneurysmal subarachnoid hemorrhage (SAH) and is multifactorial in etiology. While prior studies have suggested a role for matrix metalloproteinase‐9 (MMP‐9) in early brain injury after SAH, its contributi...
Autores principales: | Vellimana, Ananth K., Zhou, Meng‐Liang, Singh, Itender, Aum, Diane J., Nelson, James W., Harris, Glenn R., Athiraman, Umeshkumar, Han, Byung H., Zipfel, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740245/ https://www.ncbi.nlm.nih.gov/pubmed/29296615 http://dx.doi.org/10.1002/acn3.492 |
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