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Automated One-pot Radiosynthesis of [(11)C]S-adenosyl Methionine

BACKGROUND: Glycine N-methyltransferase is an enzyme overexpressed in some neo-plastic tissues. It catalyses the methylation of glycine using S-adenosyl methionine (SAM or AdoM-et) as substrate. SAM is involved in a great variety of biochemical processes, including transmeth-ylation reactions. Thus,...

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Detalles Bibliográficos
Autores principales: Zoppolo, Florencia, Porcal, Williams, Oliver, Patricia, Savio, Eduardo, Engler, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740492/
https://www.ncbi.nlm.nih.gov/pubmed/28721805
http://dx.doi.org/10.2174/1874471010666170718171441