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Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis

Kinetochores are superprotein complexes that orchestrate chromosome segregation via a dynamic interaction with spindle microtubules. A physical connection between CENP-C and the Mis12–Ndc80–Knl1 (KMN) protein network is an important pathway that is used to assemble kinetochores on CENP-A nucleosomes...

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Detalles Bibliográficos
Autores principales: Zhou, Xing, Zheng, Fan, Wang, Chengliang, Wu, Minhao, Zhang, Xiaozhen, Wang, Qian, Yao, Xuebiao, Fu, Chuanhai, Zhang, Xuan, Zang, Jianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740674/
https://www.ncbi.nlm.nih.gov/pubmed/29180432
http://dx.doi.org/10.1073/pnas.1710506114