Suppression of Alzheimer's disease-related phenotypes by the heat shock protein 70 inducer, geranylgeranylacetone, in APP/PS1 transgenic mice via the ERK/p38 MAPK signaling pathway

HSP70 overexpression has a remedying effect in neurodegenerative diseases. In Alzheimer's disease (AD), the suppressive effects of HSP70 overexpression on AD-related phenotypes and the underlying mechanisms are unknown. In the current study, the effect of geranylgeranylacetone (GGA), a non-toxi...

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Detalles Bibliográficos
Autores principales: Sun, Yuan, Zhang, Jiang-Rong, Chen, Shuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740803/
https://www.ncbi.nlm.nih.gov/pubmed/29285052
http://dx.doi.org/10.3892/etm.2017.5253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740803/
https://www.ncbi.nlm.nih.gov/pubmed/29285052
http://dx.doi.org/10.3892/etm.2017.5253

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