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Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application

BACKGROUND: Chromatin immunoprecipitation-sequencing (ChIP-seq) is a widely used epigenetic approach for investigating genome-wide protein-DNA interactions in cells and tissues. The approach has been relatively well established but several key steps still require further improvement. As a part of th...

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Detalles Bibliográficos
Autores principales: Zhong, Jian, Ye, Zhenqing, Lenz, Samuel W., Clark, Chad R., Bharucha, Adil, Farrugia, Gianrico, Robertson, Keith D., Zhang, Zhiguo, Ordog, Tamas, Lee, Jeong-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740926/
https://www.ncbi.nlm.nih.gov/pubmed/29268714
http://dx.doi.org/10.1186/s12864-017-4371-5