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Deep sequencing of natural and experimental populations of Drosophila melanogaster reveals biases in the spectrum of new mutations

Mutations provide the raw material of evolution, and thus our ability to study evolution depends fundamentally on having precise measurements of mutational rates and patterns. We generate a data set for this purpose using (1) de novo mutations from mutation accumulation experiments and (2) extremely...

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Detalles Bibliográficos
Autores principales: Assaf, Zoe June, Tilk, Susanne, Park, Jane, Siegal, Mark L., Petrov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741049/
https://www.ncbi.nlm.nih.gov/pubmed/29079675
http://dx.doi.org/10.1101/gr.219956.116