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Deep learning of the regulatory grammar of yeast 5′ untranslated regions from 500,000 random sequences
Our ability to predict protein expression from DNA sequence alone remains poor, reflecting our limited understanding of cis-regulatory grammar and hampering the design of engineered genes for synthetic biology applications. Here, we generate a model that predicts the protein expression of the 5′ unt...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741052/ https://www.ncbi.nlm.nih.gov/pubmed/29097404 http://dx.doi.org/10.1101/gr.224964.117 |