Cargando…
Metal-Dependent DNA Recognition and Cell Internalization of Designed, Basic Peptides
[Image: see text] A fragment of the DNA basic region (br) of the GCN4 bZIP transcription factor has been modified to include two His residues at designed i and i+4 positions of its N-terminus. The resulting monomeric peptide (brHis(2)) does not bind to its consensus target DNA site (5′-GTCAT-3′). Ho...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741177/ https://www.ncbi.nlm.nih.gov/pubmed/29056048 http://dx.doi.org/10.1021/jacs.7b07422 |