TFIIH generates a six base-pair open complex during RNAP II transcription initiation and start-site scanning

Eukaryotic mRNA transcription initiation is directed by the formation of the megaDalton-sized pre-initiation complex (PIC). After PIC formation, double-stranded DNA is unwound to form a single-stranded DNA bubble and the template strand is loaded into the polymerase active site. DNA opening is catal...

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Detalles Bibliográficos
Autores principales: Tomko, Eric J., Fishburn, James, Hahn, Steven, Galburt, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741190/
https://www.ncbi.nlm.nih.gov/pubmed/29106413
http://dx.doi.org/10.1038/nsmb.3500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741190/
https://www.ncbi.nlm.nih.gov/pubmed/29106413
http://dx.doi.org/10.1038/nsmb.3500

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