Quantification of huntingtin protein species in Huntington’s disease patient leukocytes using optimised electrochemiluminescence immunoassays

BACKGROUND: Huntington’s disease (HD) is an autosomal dominant neurodegenerative condition caused by an expanded CAG repeat in the gene encoding huntingtin (HTT). Optimizing peripheral quantification of huntingtin throughout the course of HD is valuable not only to illuminate the natural history and...

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Detalles Bibliográficos
Autores principales: Hensman Moss, Davina J., Robertson, Nicola, Farmer, Ruth, Scahill, Rachael I., Haider, Salman, Tessari, Michela A., Flynn, Geraldine, Fischer, David F., Wild, Edward J., Macdonald, Douglas, Tabrizi, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741241/
https://www.ncbi.nlm.nih.gov/pubmed/29272284
http://dx.doi.org/10.1371/journal.pone.0189891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741241/
https://www.ncbi.nlm.nih.gov/pubmed/29272284
http://dx.doi.org/10.1371/journal.pone.0189891

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