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Genomic alterations during p53-dependent apoptosis induced by γ-irradiation of Molt-4 leukemia cells

Molt-4 leukemia cells undergo p53-dependent apoptosis accompanied by accumulation of de novo ceramide after 14 hours of γ-irradiation. In order to identify the potential mediators involved in ceramide accumulation and the cell death response, differentially expressed genes were identified by Affymet...

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Detalles Bibliográficos
Autores principales: Hage-Sleiman, Rouba, Bahmad, Hisham, Kobeissy, Hadile, Dakdouk, Zeinab, Kobeissy, Firas, Dbaibo, Ghassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741252/
https://www.ncbi.nlm.nih.gov/pubmed/29272311
http://dx.doi.org/10.1371/journal.pone.0190221