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The dark side of opioids in pain management: basic science explains clinical observation
INTRODUCTION: In the past 2 decades, opioids have been used increasingly for the treatment of persistent pain, and doses have tended to creep up. As basic science elucidates mechanisms of pain and analgesia, the cross talk between central pain and opioid actions becomes clearer. OBJECTIVES: We aimed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Wolters Kluwer
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741356/ https://www.ncbi.nlm.nih.gov/pubmed/29392193 http://dx.doi.org/10.1097/PR9.0000000000000570 |