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Vitamin D derivatives potentiate the anticancer and anti-angiogenic activity of tyrosine kinase inhibitors in combination with cytostatic drugs in an A549 non-small cell lung cancer model

Numerous in vitro and in vivo studies have demonstrated that calcitriol [1,25(OH)(2)D(3)] and different vitamin D analogs possess antineoplastic activity, regulating proliferation, differentiation and apoptosis, as well as angiogenesis. Vitamin D compounds have been shown to exert synergistic effect...

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Detalles Bibliográficos
Autores principales: Maj, Ewa, Filip-Psurska, Beata, Milczarek, Magdalena, Psurski, Mateusz, Kutner, Andrzej, Wietrzyk, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741374/
https://www.ncbi.nlm.nih.gov/pubmed/29345296
http://dx.doi.org/10.3892/ijo.2017.4228