EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo

Despite a well-established role for the epidermal growth factor receptor (EGFR) in tumorigenesis, EGFR activities and endocytosis in tumors in vivo have not been studied. We labeled endogenous EGFR with GFP by genome-editing of human oral squamous cell carcinoma cells, which were used to examine EGF...

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Detalles Bibliográficos
Autores principales: Pinilla-Macua, Itziar, Grassart, Alexandre, Duvvuri, Umamaheswar, Watkins, Simon C, Sorkin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741375/
https://www.ncbi.nlm.nih.gov/pubmed/29268862
http://dx.doi.org/10.7554/eLife.31993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741375/
https://www.ncbi.nlm.nih.gov/pubmed/29268862
http://dx.doi.org/10.7554/eLife.31993

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