A PERK-miR211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival

The Unfolded Protein Response (UPR), is a stress activated signaling pathway that regulates cell proliferation, metabolism and survival. The circadian clock coordinates metabolism and signal transduction with light/dark cycles. We have explored how UPR signaling interfaces with the circadian clock....

Descripción completa

Detalles Bibliográficos
Autores principales: Bu, Yiwen, Yoshida, Akihiro, Chitnis, Nilesh, Altman, Brian J., Tameire, Feven, Oran, Amanda, Gennaro, Victoria, Armeson, Kent E., McMahon, Steven, Wertheim, Gerald B., Van Dang, Chi, Ruggero, Davide, Koumenis, Constantinos, Fuchs, Serge Y., Diehl, J. Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741512/
https://www.ncbi.nlm.nih.gov/pubmed/29230015
http://dx.doi.org/10.1038/s41556-017-0006-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741512/
https://www.ncbi.nlm.nih.gov/pubmed/29230015
http://dx.doi.org/10.1038/s41556-017-0006-y

Ejemplares similares