Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism

Serine proteases (SPs) are typically synthesized as precursors, termed proenzymes or zymogens, and the fully active form is produced via limited proteolysis by another protease or by autoactivation. The lectin pathway of the complement system is initiated by mannose-binding lectin (MBL)-associated S...

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Detalles Bibliográficos
Autores principales: Oroszlán, Gábor, Dani, Ráhel, Szilágyi, András, Závodszky, Péter, Thiel, Steffen, Gál, Péter, Dobó, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741598/
https://www.ncbi.nlm.nih.gov/pubmed/29326707
http://dx.doi.org/10.3389/fimmu.2017.01821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741598/
https://www.ncbi.nlm.nih.gov/pubmed/29326707
http://dx.doi.org/10.3389/fimmu.2017.01821

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