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The opposing forces of shear flow and sphingosine-1-phosphate control marginal zone B cell shuttling
Splenic marginal zone B cells (MZB) shuttle between the blood-filled marginal zone for antigen collection and the follicle for antigen delivery. However, it is unclear how MZBs migrate directionally from the marginal zone to the follicle. Here, we show that murine MZBs migrate up shear flow via the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741619/ https://www.ncbi.nlm.nih.gov/pubmed/29273735 http://dx.doi.org/10.1038/s41467-017-02482-4 |