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Structure of a Wbl protein and implications for NO sensing by M. tuberculosis

Mycobacterium tuberculosis causes pulmonary tuberculosis (TB) and claims ~1.8 million human lives per annum. Host nitric oxide (NO) is important in controlling TB infection. M. tuberculosis WhiB1 is a NO-responsive Wbl protein (actinobacterial iron–sulfur proteins first identified in the 1970s). Unt...

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Detalles Bibliográficos
Autores principales: Kudhair, Bassam K., Hounslow, Andrea M., Rolfe, Matthew D., Crack, Jason C., Hunt, Debbie M., Buxton, Roger S., Smith, Laura J., Le Brun, Nick E., Williamson, Michael P., Green, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741622/
https://www.ncbi.nlm.nih.gov/pubmed/29273788
http://dx.doi.org/10.1038/s41467-017-02418-y