Cargando…

Structure of a Wbl protein and implications for NO sensing by M. tuberculosis

Mycobacterium tuberculosis causes pulmonary tuberculosis (TB) and claims ~1.8 million human lives per annum. Host nitric oxide (NO) is important in controlling TB infection. M. tuberculosis WhiB1 is a NO-responsive Wbl protein (actinobacterial iron–sulfur proteins first identified in the 1970s). Unt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kudhair, Bassam K., Hounslow, Andrea M., Rolfe, Matthew D., Crack, Jason C., Hunt, Debbie M., Buxton, Roger S., Smith, Laura J., Le Brun, Nick E., Williamson, Michael P., Green, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741622/ https://www.ncbi.nlm.nih.gov/pubmed/29273788 http://dx.doi.org/10.1038/s41467-017-02418-y

Ejemplares similares

Interaction of the Streptomyces Wbl protein WhiD with the principal sigma factor σ(HrdB) depends on the WhiD [4Fe-4S] cluster
por: Stewart, Melissa Y. Y., et al.
Publicado: (2020)

Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence
por: Smith, Laura J., et al.
Publicado: (2017)

Sensing mechanisms of iron–sulfur cluster regulatory proteins elucidated using native mass spectrometry
por: Crack, Jason C., et al.
Publicado: (2021)

The actinobacterial WhiB‐like (Wbl) family of transcription factors
por: Bush, Matthew J.
Publicado: (2018)

WblA, a global regulator of antibiotic biosynthesis in Streptomyces
por: Nah, Hee-Ju, et al.
Publicado: (2021)

Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2
por: Stapleton, Melanie R., et al.
Publicado: (2012)

Long range transcriptional control of virulence critical genes in Mycobacterium tuberculosis by nucleoid-associated proteins?
por: Buxton, Roger S., et al.
Publicado: (2012)

The Di-Iron Protein YtfE Is a Nitric Oxide-Generating Nitrite Reductase Involved in the Management of Nitrosative Stress
por: Crack, Jason C., et al.
Publicado: (2022)

Influence of association state and DNA binding on the O(2)-reactivity of [4Fe-4S] fumarate and nitrate reduction (FNR) regulator
por: Crack, Jason C., et al.
Publicado: (2014)

Patterned Neuroprotection in the Inpp4a(wbl) Mutant Mouse Cerebellum Correlates with the Expression of Eaat4
por: Sachs, Andrew J., et al.
Publicado: (2009)

Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes
por: Lu, Cheng, et al.
Publicado: (2015)

Mechanistic Insight into the Nitrosylation of the [4Fe−4S] Cluster of WhiB-like Proteins
por: Crack, Jason C., et al.
Publicado: (2010)

Mycobacterium tuberculosis cAMP Receptor Protein (Rv3676) Differs from the Escherichia coli Paradigm in Its cAMP Binding and DNA Binding Properties and Transcription Activation Properties
por: Stapleton, Melanie, et al.
Publicado: (2010)

Three Pseudomonas putida FNR Family Proteins with Different Sensitivities to O(2)
por: Ibrahim, Susan A., et al.
Publicado: (2015)

wblE2 transcription factor in Streptomyces griseus S4‐7 plays an important role in plant protection
por: Cho, Hyun Ji, et al.
Publicado: (2017)

Mass spectrometric detection of iron nitrosyls, sulfide oxidation and mycothiolation during nitrosylation of the NO sensor [4Fe–4S] NsrR
por: Crack, Jason C., et al.
Publicado: (2018)

Reprogramming of Escherichia coli K-12 Metabolism during the Initial Phase of Transition from an Anaerobic to a Micro-Aerobic Environment
por: Trotter, Eleanor W., et al.
Publicado: (2011)

Generation of (34)S-substituted protein-bound [4Fe-4S] clusters using (34)S-L-cysteine
por: Crack, Jason C, et al.
Publicado: (2019)

The Transcriptional Repressor Protein NsrR Senses Nitric Oxide Directly via a [2Fe-2S] Cluster
por: Tucker, Nicholas P., et al.
Publicado: (2008)

A New Dioic Acid from a wbl Gene Mutant of Deepsea-Derived Streptomyces somaliensis SCSIO ZH66
por: Huang, Huiming, et al.
Publicado: (2016)

The WblC/WhiB7 Transcription Factor Controls Intrinsic Resistance to Translation-Targeting Antibiotics by Altering Ribosome Composition
por: Lee, Ju-Hyung, et al.
Publicado: (2020)

Biochemical properties of Paracoccus denitrificans FnrP: reactions with molecular oxygen and nitric oxide
por: Crack, Jason C., et al.
Publicado: (2016)

NsrR from Streptomyces coelicolor Is a Nitric Oxide-sensing [4Fe-4S] Cluster Protein with a Specialized Regulatory Function
por: Crack, Jason C., et al.
Publicado: (2015)

Activation of Cryptic Antibiotic Biosynthetic Gene Clusters Guided by RNA-seq Data from Both Streptomyces ansochromogenes and ΔwblA
por: Li, Yue, et al.
Publicado: (2021)

Mechanisms of iron- and O(2)-sensing by the [4Fe-4S] cluster of the global iron regulator RirA
por: Pellicer Martinez, Ma Teresa, et al.
Publicado: (2019)

NBP35 interacts with DRE2 in the maturation of cytosolic iron‐sulphur proteins in Arabidopsis thaliana
por: Bastow, Emma L., et al.
Publicado: (2017)

Native mass spectrometric studies of IscSU reveal a concerted, sulfur-initiated mechanism of iron–sulfur cluster assembly
por: Bennett, Sophie P., et al.
Publicado: (2022)

Genomic mapping of cAMP receptor protein (CRP(Mt)) in Mycobacterium tuberculosis: relation to transcriptional start sites and the role of CRP(Mt) as a transcription factor
por: Kahramanoglou, Christina, et al.
Publicado: (2014)

Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches()
por: Green, Jeffrey, et al.
Publicado: (2014)

Structure-Function Relationships of the Mycobacterium tuberculosis Transcription Factor WhiB1
por: Smith, Laura J., et al.
Publicado: (2012)

Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response()
por: Matange, Nishad, et al.
Publicado: (2013)

Sensing iron availability via the fragile [4Fe–4S] cluster of the bacterial transcriptional repressor RirA
por: Pellicer Martinez, Ma Teresa, et al.
Publicado: (2017)

Activation of a plasmid-situated type III PKS gene cluster by deletion of a wbl gene in deepsea-derived Streptomyces somaliensis SCSIO ZH66
por: Huang, Huiming, et al.
Publicado: (2016)

Stabilisation of the RirA [4Fe–4S] cluster results in loss of iron-sensing function
por: Gray, Elizabeth, et al.
Publicado: (2023)

Differentiated, Promoter-specific Response of [4Fe-4S] NsrR DNA Binding to Reaction with Nitric Oxide
por: Crack, Jason C., et al.
Publicado: (2016)

Characterization of a putative NsrR homologue in Streptomyces venezuelae reveals a new member of the Rrf2 superfamily
por: Munnoch, John T., et al.
Publicado: (2016)

Discovery of Antimycin-Type Depsipeptides from a wbl Gene Mutant Strain of Deepsea-Derived Streptomyces somaliensis SCSIO ZH66 and Their Effects on Pro-inflammatory Cytokine Production
por: Li, Huayue, et al.
Publicado: (2017)

In conditions of over-expression, WblI, a WhiB-like transcriptional regulator, has a positive impact on the weak antibiotic production of Streptomyces lividans TK24
por: Yan, Lan, et al.
Publicado: (2017)

Structural determinants of DNA recognition by the NO sensor NsrR and related Rrf2-type [FeS]-transcription factors
por: Rohac, Roman, et al.
Publicado: (2022)

Nitrosylation of Nitric‐Oxide‐Sensing Regulatory Proteins Containing [4Fe‐4S] Clusters Gives Rise to Multiple Iron–Nitrosyl Complexes
por: Serrano, Pauline N., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_fahpudlpr1kckms4j3egci2alm