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VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses

Glutamate is the major excitatory transmitter in the vertebrate nervous system. To maintain synaptic efficacy, recycling synaptic vesicles (SV) are refilled with glutamate by vesicular glutamate transporters (VGLUTs). The dynamics and mechanism of glutamate uptake in intact neurons are still largely...

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Detalles Bibliográficos
Autores principales: Martineau, Magalie, Guzman, Raul E., Fahlke, Christoph, Klingauf, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741633/
https://www.ncbi.nlm.nih.gov/pubmed/29273736
http://dx.doi.org/10.1038/s41467-017-02367-6