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The crucial role of the TRPM7 kinase domain in the early stage of amelogenesis

Transient receptor potential melastatin-7 (TRPM7) is a bi-functional protein containing a kinase domain fused to an ion channel. TRPM7 is highly expressed in ameloblasts during tooth development. Here we show that TRPM7 kinase-inactive knock-in mutant mice (TRPM7 KR mice) exhibited small enamel volu...

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Detalles Bibliográficos
Autores principales: Ogata, Kayoko, Tsumuraya, Tomoyuki, Oka, Kyoko, Shin, Masashi, Okamoto, Fujio, Kajiya, Hiroshi, Katagiri, Chiaki, Ozaki, Masao, Matsushita, Masayuki, Okabe, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741708/
https://www.ncbi.nlm.nih.gov/pubmed/29273814
http://dx.doi.org/10.1038/s41598-017-18291-0