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Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy

Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of γ-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. Does GHRH enhance the inhibitory effect of GABA to preven...

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Detalles Bibliográficos
Autores principales: Tang, Shirong, Luo, Zhong, Qiu, Xiaowei, Zhang, Yanke, Lu, Xi, huang, Hao, Xu, Zhongxiang, Xu, Zucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741719/
https://www.ncbi.nlm.nih.gov/pubmed/29273763
http://dx.doi.org/10.1038/s41598-017-18416-5