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Residues His172 and Lys238 are Essential for the Catalytic Activity of the Maleylacetate Reductase from Sphingobium chlorophenolicum Strain L-1

Maleylacetate reductase (PcpE), the last enzyme in the pentachlorophenol biodegradation pathway in Sphingobium chlorophenolicum L-1, catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate (2-CMA) to maleylacetate (MA) and subsequent reduction of MA to 3-oxoa...

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Detalles Bibliográficos
Autores principales: Chen, Lifeng, Krol, Ed S., Sakharkar, Meena K., Khan, Haseeb A., Alhomida, Abdullah S., Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741723/
https://www.ncbi.nlm.nih.gov/pubmed/29273747
http://dx.doi.org/10.1038/s41598-017-18475-8