Elimination of Antibiotic Resistant Surgical Implant Biofilms Using an Engineered Cationic Amphipathic Peptide WLBU2

Antibiotics are unable to remove biofilms from surgical implants. This high antibiotic tolerance is related to bacterial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a reduced metabolic state. WLBU2 is an engineered cationic amphipathic peptide designe...

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Detalles Bibliográficos
Autores principales: Mandell, Jonathan B., Deslouches, Berthony, Montelaro, Ronald C., Shanks, Robert M. Q., Doi, Yohei, Urish, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741726/
https://www.ncbi.nlm.nih.gov/pubmed/29273750
http://dx.doi.org/10.1038/s41598-017-17780-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741726/
https://www.ncbi.nlm.nih.gov/pubmed/29273750
http://dx.doi.org/10.1038/s41598-017-17780-6

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