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Elimination of Antibiotic Resistant Surgical Implant Biofilms Using an Engineered Cationic Amphipathic Peptide WLBU2
Antibiotics are unable to remove biofilms from surgical implants. This high antibiotic tolerance is related to bacterial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a reduced metabolic state. WLBU2 is an engineered cationic amphipathic peptide designe...
Autores principales: | Mandell, Jonathan B., Deslouches, Berthony, Montelaro, Ronald C., Shanks, Robert M. Q., Doi, Yohei, Urish, Kenneth L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741726/ https://www.ncbi.nlm.nih.gov/pubmed/29273750 http://dx.doi.org/10.1038/s41598-017-17780-6 |
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