Donepezil suppresses intracellular Ca(2+) mobilization through the PI3K pathway in rodent microglia

BACKGROUND: Microglia are resident innate immune cells which release many factors including proinflammatory cytokines or nitric oxide (NO) when they are activated in response to immunological stimuli. Pathophysiology of Alzheimer’s disease (AD) is related to the inflammatory responses mediated by mi...

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Detalles Bibliográficos
Autores principales: Haraguchi, Yoshinori, Mizoguchi, Yoshito, Ohgidani, Masahiro, Imamura, Yoshiomi, Murakawa-Hirachi, Toru, Nabeta, Hiromi, Tateishi, Hiroshi, Kato, Takahiro A., Monji, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741946/
https://www.ncbi.nlm.nih.gov/pubmed/29273047
http://dx.doi.org/10.1186/s12974-017-1033-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741946/
https://www.ncbi.nlm.nih.gov/pubmed/29273047
http://dx.doi.org/10.1186/s12974-017-1033-0

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