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Practical considerations for choosing a mouse model of Alzheimer’s disease
Alzheimer’s disease (AD) is behaviorally identified by progressive memory impairment and pathologically characterized by the triad of β-amyloid plaques, neurofibrillary tangles, and neurodegeneration. Genetic mutations and risk factors have been identified that are either causal or modify the diseas...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741956/ https://www.ncbi.nlm.nih.gov/pubmed/29273078 http://dx.doi.org/10.1186/s13024-017-0231-7 |