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Practical considerations for choosing a mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is behaviorally identified by progressive memory impairment and pathologically characterized by the triad of β-amyloid plaques, neurofibrillary tangles, and neurodegeneration. Genetic mutations and risk factors have been identified that are either causal or modify the diseas...

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Detalles Bibliográficos
Autores principales: Jankowsky, Joanna L., Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741956/
https://www.ncbi.nlm.nih.gov/pubmed/29273078
http://dx.doi.org/10.1186/s13024-017-0231-7