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Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

BACKGROUND: The genomes of laboratory rat strains are characterised by a mosaic haplotype structure caused by their unique breeding history. These mosaic haplotypes have been recently mapped by extensive sequencing of key strains. Comparison of genomic variation between two closely related rat strai...

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Detalles Bibliográficos
Autores principales: Martín-Gálvez, David, Dunoyer de Segonzac, Denis, Ma, Man Chun John, Kwitek, Anne E., Thybert, David, Flicek, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741965/
https://www.ncbi.nlm.nih.gov/pubmed/29272997
http://dx.doi.org/10.1186/s12864-017-4351-9