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Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat
BACKGROUND: The genomes of laboratory rat strains are characterised by a mosaic haplotype structure caused by their unique breeding history. These mosaic haplotypes have been recently mapped by extensive sequencing of key strains. Comparison of genomic variation between two closely related rat strai...
Autores principales: | Martín-Gálvez, David, Dunoyer de Segonzac, Denis, Ma, Man Chun John, Kwitek, Anne E., Thybert, David, Flicek, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741965/ https://www.ncbi.nlm.nih.gov/pubmed/29272997 http://dx.doi.org/10.1186/s12864-017-4351-9 |
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