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Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis

Various growth factors regulate synapse development and neurogenesis, and are essential for brain function. Changes in growth factor signaling are implicated in many neuropsychiatric disorders such as depression, autism and epilepsy. We have previously identified that fibroblast growth factor 22 (FG...

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Detalles Bibliográficos
Autores principales: Terauchi, Akiko, Gavin, Elizabeth, Wilson, Julia, Umemori, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742095/
https://www.ncbi.nlm.nih.gov/pubmed/29311892
http://dx.doi.org/10.3389/fnsyn.2017.00017