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Neoantigen Targeting—Dawn of a New Era in Cancer Immunotherapy?

During their development and progression tumors acquire numerous mutations that, when translated into proteins give rise to neoantigens that can be recognized by T cells. Initially, neoantigens were not recognized as preferred targets for cancer immunotherapy due to their enormous diversity and the...

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Detalles Bibliográficos
Autores principales: Wirth, Thomas C., Kühnel, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742119/
https://www.ncbi.nlm.nih.gov/pubmed/29312332
http://dx.doi.org/10.3389/fimmu.2017.01848