Public Clonotypes and Convergent Recombination Characterize the Naïve CD8(+) T-Cell Receptor Repertoire of Extremely Preterm Neonates

Respiratory support improvements have aided survival of premature neonates, but infection susceptibility remains a predominant problem. We previously reported that neonatal mice have a rapidly evolving T-cell receptor (TCR) repertoire that impairs CD8(+) T cell immunity. To understand the impact of...

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Detalles Bibliográficos
Autores principales: Carey, Alison J., Hope, Jennifer L., Mueller, Yvonne M., Fike, Adam J., Kumova, Ogan K., van Zessen, David B. H., Steegers, Eric A. P., van der Burg, Mirjam, Katsikis, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742125/
https://www.ncbi.nlm.nih.gov/pubmed/29312340
http://dx.doi.org/10.3389/fimmu.2017.01859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742125/
https://www.ncbi.nlm.nih.gov/pubmed/29312340
http://dx.doi.org/10.3389/fimmu.2017.01859

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