Lack of Adrenomedullin Aggravates Acute TNBS-Induced Colitis Symptoms in Mice, Especially in Females

Adrenomedullin (AM) is a biologically active peptide which has been tested as a new therapy for inflammatory bowel disease (IBD) in animal models and in patients with severe ulcerative colitis. We used an inducible knockout (KO) mouse model for AM to evaluate the effects of endogenous levels of this...

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Detalles Bibliográficos
Autores principales: Martínez-Herrero, Sonia, Larrayoz, Ignacio M., Narro-Íñiguez, Judit, Rubio-Mediavilla, Susana, Martínez, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742153/
https://www.ncbi.nlm.nih.gov/pubmed/29311984
http://dx.doi.org/10.3389/fphys.2017.01058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742153/
https://www.ncbi.nlm.nih.gov/pubmed/29311984
http://dx.doi.org/10.3389/fphys.2017.01058

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