Bruch’s Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the western world and affects nearly 200 million people globally. Local inflammation driven by complement system dysregulation is currently a therapeutic target. Bruch’s membrane (BrM) is a sheet of extracellular matrix that...

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Detalles Bibliográficos
Autores principales: Clark, Simon J., McHarg, Selina, Tilakaratna, Viranga, Brace, Nicole, Bishop, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742201/
https://www.ncbi.nlm.nih.gov/pubmed/29312308
http://dx.doi.org/10.3389/fimmu.2017.01778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742201/
https://www.ncbi.nlm.nih.gov/pubmed/29312308
http://dx.doi.org/10.3389/fimmu.2017.01778

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