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Bruch’s Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the western world and affects nearly 200 million people globally. Local inflammation driven by complement system dysregulation is currently a therapeutic target. Bruch’s membrane (BrM) is a sheet of extracellular matrix that...

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Detalles Bibliográficos
Autores principales:	Clark, Simon J., McHarg, Selina, Tilakaratna, Viranga, Brace, Nicole, Bishop, Paul N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742201/ https://www.ncbi.nlm.nih.gov/pubmed/29312308 http://dx.doi.org/10.3389/fimmu.2017.01778

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