Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice

Neuronal degeneration following traumatic brain injury (TBI) leads to intracellular accumulation of dysfunctional proteins and organelles. Autophagy may serve to facilitate degradation to overcome protein debris load and therefore be an important pro-survival factor. On the contrary, clearing may se...

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Detalles Bibliográficos
Autores principales: Sebastiani, Anne, Gölz, Christina, Sebastiani, Philipp G., Bobkiewicz, Wiesia, Behl, Christian, Mittmann, Thomas, Thal, Serge C., Engelhard, Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742218/
https://www.ncbi.nlm.nih.gov/pubmed/29311767
http://dx.doi.org/10.3389/fnins.2017.00678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742218/
https://www.ncbi.nlm.nih.gov/pubmed/29311767
http://dx.doi.org/10.3389/fnins.2017.00678

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