Both Systemic and Intra-articular Immunization with Citrullinated Peptides Are Needed to Induce Arthritis in the Macaque

OBJECTIVES: Anti-citrullinated peptides antibodies (ACPAs) have high specificity for the diagnosis of rheumatoid arthritis (RA), but their role in the pathophysiology is not fully established. The main genetic risk factor for RA, the shared epitope in major histocompatibility complex class II, is as...

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Detalles Bibliográficos
Autores principales: Bitoun, Samuel, Roques, Pierre, Larcher, Thibaut, Nocturne, Gaétane, Serguera, Che, Chrétien, Pascale, Serre, Guy, Grand, Roger Le, Mariette, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742322/
https://www.ncbi.nlm.nih.gov/pubmed/29326703
http://dx.doi.org/10.3389/fimmu.2017.01816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742322/
https://www.ncbi.nlm.nih.gov/pubmed/29326703
http://dx.doi.org/10.3389/fimmu.2017.01816

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