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The Role of Heparin Cofactor II in the Regulation of Insulin Sensitivity and Maintenance of Glucose Homeostasis in Humans and Mice

Aim: Accelerated thrombin action is associated with insulin resistance. It is known that upon activation by binding to dermatan sulfate proteoglycans, heparin cofactor II (HCII) inactivates thrombin in tissues. Because HCII may be involved in glucose metabolism, we investigated the relationship betw...

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Detalles Bibliográficos
Autores principales: Kurahashi, Kiyoe, Inoue, Seika, Yoshida, Sumiko, Ikeda, Yasumasa, Morimoto, Kana, Uemoto, Ryoko, Ishikawa, Kazue, Kondo, Takeshi, Yuasa, Tomoyuki, Endo, Itsuro, Miyake, Masato, Oyadomari, Seiichi, Matsumoto, Toshio, Abe, Masahiro, Sakaue, Hiroshi, Aihara, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742367/
https://www.ncbi.nlm.nih.gov/pubmed/28502917
http://dx.doi.org/10.5551/jat.37739