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Urinary and Serum Metabolomics Analyses Uncover That Total Glucosides of Paeony Protect Liver against Acute Injury Potentially via Reprogramming of Multiple Metabolic Pathways

Total glucosides of paeony (TGP) have been confirmed to be hepatoprotective. However, the underlying mechanism is largely unclear. In this study, we investigated the metabolic profiles of urine and serum in rats with carbon tetrachloride- (CCl(4)-) induced experimental liver injury and TGP administr...

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Detalles Bibliográficos
Autores principales: Li, Haojie, Cao, Wenli, Lu, Mengxi, Wu, Chunxiao, Wang, Xinguo, Niu, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742450/
https://www.ncbi.nlm.nih.gov/pubmed/29375644
http://dx.doi.org/10.1155/2017/9038260