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Ca(2+) activity signatures of myelin sheath formation and growth in vivo
During myelination, individual oligodendrocytes initially over-produce short myelin sheaths that are either retracted or stabilised. By live imaging oligodendrocyte Ca(2+) activity in vivo, we find that high-amplitude long-duration Ca(2+) transients in sheaths prefigure retractions, mediated by calp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742537/ https://www.ncbi.nlm.nih.gov/pubmed/29230058 http://dx.doi.org/10.1038/s41593-017-0040-x |